X-TubeProcessor®

Smart 2.0

Compact 3-in-1 automation for flexible tube processing — now with X-Control.

The X-TubeProcessor®_Smart 2.0 is the next generation of compact laboratory automation — dispensing, labeling, and capping in a single system. It combines proven precision with key innovations:

It now processes tubes and vials in the volume range of 0.5–15 ml without any gripper change, supports different and configurable workflows, and – with the X-Control software – offers numerous new functions in the areas of user management and audit trail for operation in regulated environments.

In combination with the TwinCode barcoding system, the Smart 2.0 now enables tube-specific dispensing and labeling as well as seamless traceability of every single tube.

With a footprint of less than < 1 m², capacity for up to 6 SBS-format racks, and a processing speed of up to 370 tubes per hour, the Smart 2.0 is the ideal solution for laboratories looking to increase efficiency, traceability and reproducible quality – from routine applications to QC, from diagnostics to biotech.

The return on investment is typically achieved in under two years – based on an average reduction of manual work by 4 hours per day for 2 employees.

What’s new with the Smart 2.0?

The Smart 2.0 is based on the proven Smart system and has been newly equipped with the X-Control software. It enables greater flexibility in terms of supported tube and vial formats while simultaneously providing extended process and processing control. In addition, hardware options such as TwinCode and the choice of a microannular gear pump ensure increased precision and adaptability to the workflow – especially for regulated and digitally integrated laboratory environments and specialized dispensing requirements.

  • gnificantly expanded processing range
    Simultaneous processing of 0.5–15 ml tubes and vials – including cryovials, biobank tubes, HPLC vials, and FACS tubes.

  • New X-Control software platform
    A unified software base shared with the X-TubeProcessor®_Sign, featuring significantly simplified and clearer job creation as well as new functions for dispensing, capping, and TwinCode logic – complemented by easy management of labware and racks.

  • Seamless system integration
    REST/API interface for connection to ERP and LIMS systems, enabling end-to-end digital workflows.

  • Increased efficiency in everyday laboratory work
    Capacity for up to 6 SBS-format racks enabling long walkaway times, processing speeds of up to 370 tubes per hour, and a significantly reduced level of manual effort.

  • TwinCode barcoding system
    Tube-specific processing based on two barcodes (e.g., for labeling and dispensing), enabling clear identification, full traceability, and automated process decisions – including tube-specific positioning within the rack.

  • New microannular gear pump
    Higher dosing precision and process stability, especially for demanding liquids and small volumes—also available with a peristaltic pump as an alternative.

  • Modern job and user management
    Local and decentralized job management with user management and audit trail functionality—a key prerequisite for use in regulated environments.

The Smart 2.0 is more than just an upgrade. It has been specifically designed for greater flexibility and simple, intuitive operation, and supports workflows in regulated laboratory environments far more comprehensively than its predecessor.

Laboratories benefit from clearly structured workflows, high user-friendliness, and a noticeable reduction in manual work by several hours per day.

Proven automation in molecular diagnostics

At PathoFinder, the X-TubeProcessor®_Smart is used in core production workflows for dispensing, labeling, and capping under strict quality requirements.

The system supports reliable, traceable processes while significantly reducing manual supervision and freeing skilled staff for higher-value tasks.

This enables PathoFinder to increase capacity and prepare for future growth without compromising quality.

Automation in the smallest footprint – flexible and reliable

With the X-TubeProcessor®_Smart 2.0, you automate time-consuming routine processes related to screw-cap tubes: From precise dispensing to secure capping/decapping and validated labeling, the system performs complete workflows without manual intervention. The optional HEPA filter ensures a sterile working environment.

Here’s how the X-TubeProcessor®_Smart 2.0 works, step by step:

Digital order processing & material testing

Load tubes

Up to 6 SBS racks simultaneously—for long walk-away times and high productivity.

Automatic removal from refrigerated storage

Automatic opening & closing

Capping and decapping of 0.5–15 ml tubes & vials with Torque control and rotational movement monitoring for reproducible results. .

Precise dispensing & filling with screw connection

Precise filling

Optional peristaltic pump or micro annular gear pump. Routine functions are controlled via the DosingPumpManager.

Integrated labeling

Labeling & validation

Automatic positioning and labeling; optional label verification via TwinCode. Label templates with dynamic additional information (lot no., expiry date); can be used as a network printer.

Digital documentation & traceability

Sort & Store

Structured downstream processing and storage of tubes – ideal for serial and batch workflows.

Finished products can be removed at any time

X-Control

Intelligent, auditable job & process management: planning, documentation, and control of all workflows – locally or remotely.

Voices from the field

Brett Clark, Production Manager at Genetic Signatures

“We needed equipment that could be easily integrated into our production schedule. HTI delivered a solution that requires very little space – and fits our processes perfectly.”

Brett Clark,
Production Manager at Genetic Signatures, Sydney

“Quality and reproducibility are critical for us. We were looking for a compact system that reliably fills and caps while offering maximum walk-away time – and we found it in the Smart.”

Dr. Martin Käsemann,
COO, PreOmics

All functional modules of the Smart 2.0

Tube Handling incl. Capping & Decapping
Automated opening and closing of a wide range of tubes and vials from 0.5 to 15 ml. Monitoring of rotational movement ensures reproducible results and reduces manual errors – independent of tube size and application.

Precise dispensing with two pump technologies
Depending on application requirements, either a peristaltic pump for dispensing without media contact with fast tube changes, or an optional micro annular gear pump for maximum dosing accuracy and stability is available. Both pumps are centrally controlled via the DosingPumpManager, including priming, cleaning, and calibration functions.

Labeling with flexible templates and in-process control
High-resolution, automated labeling with precise positioning. Support for label templates with fixed or dynamic content (e.g. lot number, expiry date), as well as use as a network printer for existing Bartender files. Optionally, TwinCode enables additional label verification during the process.

X-Control Software – Central workflow control
Centralized job and process management for planning, control, and documentation of all workflows. X-Control supports audit trail and reporting functions and can be seamlessly integrated into existing LIMS and ERP systems via REST APIs.

Tube-specific processing and traceability with TwinCode
Processing of bottom and side barcodes for tube-specific control of dispensing, labeling, and in-process controls. All process data is uniquely assigned to each individual tube and documented in an exportable job log file – ensuring complete traceability and supporting GLP and GMP processes.

Result:
Standardized processes, reproducible results, and a compact all-in-one solution that measurably increases efficiency and quality.

X-Control – support for maximum control and compliance

X-Control turns the Smart 2.0 into an intelligent platform for controlled, transparent, and standardized workflows. The software provides features that support users in implementing GMP-, GLP-, and 21 CFR Part 11–relevant processes.

Digital order processing & material testing

Job Creation

Intuitive creation of new workflows in under three minutes – locally or remotely.

  • Clear, logically structured process steps (dispensing, capping, labeling, barcode-reading)
  • Recipe functions & variable inputs (number of tubes, fill volume, etc.)
  • High flexibility through combinable process steps
  • Job templates for standardized and reproducible workflows
  • Support for various tube & vial types as well as liquid classes
Digital order processing & material testing

Job Management

Plan, manage, and execute workflows – on the device or remotely.

  • Color status system (green/blue/red) for job status and required labware
  • Management of all components: racks, tubes, labels, caps
  • Data import from Excel, ERP, or LIMS
  • Seamless system integration via REST API
  • Ideal for end-to-end digitization and automated routine workflows
Digital order processing & material testing

Control & governance

Compliant and traceable process execution.

  • User management: roles & permissions for clear, documented governance
  • Audit trail & LogViewer: complete logging of all actions with timestamps
  • Export functions (PDF/CSV) and optional database access for in-depth analysis
  • System information: notifications, statistics, device status & language settings
  • Maximum transparency for regulated laboratory environments
Digital order processing & material testing

Labware & Pump

Centralized management of all labware and pump processes

  • Management of racks, tubes, caps & labels
  • LabwareManager Pro: Enables flexible creation of additional usable labware
  • Dosing Pump Manager: priming, cleaning & calibration of the pump
  • Management & creation of custom liquid classes
  • Teaching Wizard for fast onboarding of device-specific components

Areas of application:

The X-TubeProcessor®_Smart 2.0 is ideal for laboratories looking to automate repetitive routine processes, reduce manual errors, and simultaneously increase flexibility, transparency, and process reliability – particularly for small to medium volumes.

It is particularly suited for applications where:

  • Manual tube-based routine tasks such as opening, filling, labeling, and documentation tie up time and personnel.

  • different tube and vial formats (0.5–15 ml) need to be processed within a single system.

  • reproducible results and standardized workflows are required.

  • compliance requirements (GxP, GLP, GMP) need to be supported by audit trail functionality, user management, and seamless documentation.

  • tube-specific processes are to be controlled via barcodes and fully traceable.

  • limited laboratory space needs to be optimally utilized with a compact, high-performance all-in-one automation solution.

  • LIMS- or ERP-driven workflows require centralized, software-based control.

Typical fields of application:
The Smart 2.0 is used, among others, in:
Diagnostics · Life science services · Biotechnology · Pharma · Environmental laboratories · Biobanking · Research & Development · QC laboratories

Benefits of laboratory automation with the X-TubeProcessor®_Smart 2.0

  • Compact & quiet: Small footprint of less than 1 m²—ideal for use directly on the lab bench, with no additional infrastructure required.

  • Processing of 0.5–15 ml tubes and vials:
    Adaptation to different application requirements through configurable options such as a cap feeder, as well as the choice between a peristaltic pump or a micro annular gear pump.

  • Secure & reproducible: Controlled process steps, optional TwinCode verification, and continuous, auditable documentation support consistent results and regulated laboratory workflows.

  • Efficient in everyday laboratory work: High throughput of up to 370 tubes per hour and long walkaway times significantly relieve staff from repetitive routine tasks.

  • Intelligently controlled: The X-Control software enables centralized job and process management, supports GxP-relevant workflows, and can be integrated into existing LIMS or ERP systems.

Frequently Asked Questions about X-TubeProcessor®_Smart 2.0

What applications is Smart 2.0 suitable for?

The X-TubeProcessor®_Smart 2.0 is designed for laboratories looking to automate repetitive tube-based routine work while increasing flexibility, transparency and process reliability.

The system is particularly suitable for:

  • automated dispensing & filling
  • Capping & Decapping
  • automated tube labeling
  • standardized tube processing workflows
  • kit production and reagent manufacturing
  • diagnostic and biobanking workflows
  • regulated laboratory environments
  • small to medium volumes
  • LIMS- and ERP-supported processes

By combining tube handling, liquid handling, labeling and digital process control, Smart 2.0 supports standardized and reproducible laboratory workflows in a compact all-in-one solution.

Smart 2.0 combines multiple tube processing steps in one compact system, including:

  • dispensing & filling
  • Capping & Decapping
  • automated labeling
  • barcode-based tube identification
  • digital process control

The individual process steps can be combined flexibly and adapted to different laboratory workflows. This helps reduce manual work steps and supports standardized processes.

Yes, Smart 2.0 processes different tube and vial types from 0.5 ml to 15 ml without requiring a gripper change.

Supported tube types include:

  • Cryovials
  • Biobank tubes
  • HPLC vials
  • FACS tubes
  • Blood collection tubes
  • Conical tubes

The system supports different tube formats within a standardized workflow.

Smart 2.0 supports:

  • Tube and vial sizes from 0.5–15 mL
  • Tube diameters from 7–22 mm
  • Tube heights up to 65 mm

Additional tube types are available on request.

Two pump technologies are available for Smart 2.0:

  • Peristaltic pump
  • Micro annular gear pump

The peristaltic pump is particularly suitable for robust and flexible standard dispensing applications, offering fast tube changes and dispensing without medium contact.

The optional micro annular gear pump provides very high dosing accuracy and process stability, especially for small volumes, precise filling applications and demanding liquids.

Depending on the workflow and application requirements, the appropriate pump technology can be selected.

Smart 2.0 supports precise and reproducible filling and dispensing processes. The optional micro annular gear pump was specifically designed for very high dosing accuracy and stable processes, particularly for small volumes.

The DosingPumpManager supports important routine functions, including:

  • Priming
  • Cleaning
  • Calibration
  • Management of different liquid classes

This helps support standardized and reproducible dispensing processes.

Smart 2.0 can process up to 6 SBS racks within an automated workflow. The tubes are pre-loaded into racks and then processed automatically. Depending on rack capacity and workflow, long walkaway times of up to almost 3 hours are possible.

Depending on the workflow, Smart 2.0 achieves throughput rates of up to 370 tubes per hour.

Typical processing speeds include:

  • up to 360 tubes/h – labeling
  • up to 303 tubes/h – dispensing + capping
  • up to 180 tubes/h – 3-in-1 processing

The actual throughput depends on factors such as the workflow, tube type and process combination.

Smart 2.0 supports up to 6 SBS racks in its standard configuration within an automated workflow.
Depending on the size and type of tubes used, the capacity varies:

  • 18 tubes per rack for 15 ml Falcon tubes
  • up to 96 micro screw tubes per rack

Depending on the rack type and workflow, this results in a total capacity of up to 576 tubes per run.
In addition, Smart 2.0 supports mixed configurations with different rack types within a single workflow.

Yes, Smart 2.0 supports sterile working environments through features such as:

  • HEPA filter
  • controlled process execution
  • standardized workflows

This helps support sensitive filling and tube processing applications.

To help reduce contamination risks, Smart 2.0 supports:

  • controlled and standardized processes
  • automated and closed workflow sequences
  • reproducible dispensing processes
  • defined cleaning and flushing procedures
  • HEPA-filtered working environments
  • digital process monitoring

Because opening, filling and closing are performed automatically, manual contact with tubes, caps and reagents is significantly reduced.
This helps minimize potential sources of error, cross-contamination and unnecessary process interruptions.

Smart 2.0 supports cleaning, flushing and calibration functions through the DosingPumpManager.

In addition, the software supports:

  • priming processes
  • pump cleaning
  • Management of different liquid classes
  • standardized cleaning procedures

Smart 2.0 supports controlled and standardized processes through:

  • audit trail functions
  • user management
  • digital process documentation
  • exportable job log files
  • tube-specific traceability

The X-Control software supports users in GMP-, GLP- and 21 CFR Part 11-relevant workflows.

Yes, Smart 2.0 supports integration into existing laboratory and IT infrastructures.

Connection to:

  • ERP systems
  • LIMS systems
  • digital workflow processes

is provided via REST API interfaces.
This helps support standardized and end-to-end digital processes.

Smart 2.0 was developed as a compact all-in-one solution and requires less than 1 m² of laboratory space.

Dimensions:

  • 82 × 73 × 84 cm (W × D × H)

With HEPA filter:

  • Height: approx. 115 cm
  • Weight: 72–95 kg (depending on configuration)

This makes the system suitable for laboratories with limited space.

The lead time for standard systems is typically 8 to 12 weeks.

For custom configurations or customer-specific modifications, longer lead times may apply.

Technical specifications & performance features

Info Download

Supported tubes & vials
Volumes: 0.5–15 ml
Diameter: 7–22 mm
Height: up to 65 mm
Compatibility includes: Sarstedt, Greiner, Thermo Fisher, SSI, Biozym, cryovials, biobank tubes, HPLC vials, FACS tubes, blood collection tubes, conical tubes (others available on request)

Dimensions and weight

Dimensions:
ca. 82 × 73 × 84 cm (B × T × H),
with HEPA filter 115 cm height
Approx. 32.3″ × 28.7″ × 33.1″ (W × D × H),
with HEPA filter 45.3″ height

Weight:
Approx. 158.7 – 209.4 lbs (depemdimg on configuration)
ca. 72–95 kg (konfigurationsabhängig)

Speed and capacity

Speed
Up to 370 tubes per hour (depending on workflow)
360 tubes/h labeling
303 tubes/h dispensing + capping
180 tubes/h 3-in-1 processing

Capacity:
Supply: 576 micro screw tubes
Storage: 1,152 microvials
6 SBS racks in parallel

What is the delivery time for Smart 2.0?

Consultation & contact – automate your processes now

Increase efficiency, quality, and compliance with the X-TubeProcessor®_Smart 2.0.
Request a personal live demo—available in just 5 minutes.

Lisa Mehr

Area Sales Manager

DACH region
(Germany, Austria, Switzerland)

Alan Lakshmanan

Area Sales Manager

UK, France,
non-DACH regions of Europe

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Let our specialists advise you!

We would be happy to discuss your application and automation requirements with you:
Phone: +49 08092 2092-70 or email: sales@hti-automation.com

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